The Indianapolis Colts (3-1) return to Lucas Oil Stadium for NFL Week 5 action against the Las Vegas Raiders (1-3). The Colts are tied with the Jacksonville Jaguars atop the AFC South, while the Raiders trail the AFC West.

Here's how to listen to every NFL game in Week 5 on the radio. All 32 NFL teams have their own radio networks that will broadcast every game this season across local and regional stations.

The Cardinals have had decent moments. They scored on their first two possessions. Marvin Harrison Jr., made a terrific catch, out-jumping two defenders for a 43-yard catch. But Arizona also had a chance to put this one away, and couldn't do it. The Cardinals punted on their last three possessions of the first half, letting Tennessee hang around.

The Minnesota Vikings, led by quarterback Carson Wentz, face the Cleveland Browns, led by rookie quarterback Dillon Gabriel, on Sunday, Oct. 5, 2025 at Tottenham Hotspur Stadium in London, England.

The Detroit Lions are back in action in Week 5 of the 2025 NFL season and for the third time this year, they'll face an AFC North team. It's Lions vs. Cincinnati Bengals at Paycor Stadium, where the Bengals will be without star quarterback Joe Burrow.

Week 5’s Sunday slate concludes with an AFC East battle between the Buffalo Bills and New England Patriots on “Sunday Night Football” at Highmark Stadium. Buffalo enters play with a 4-0 record, most recently beating the Saints at home. New England also won in Week 4, dominating the Panthers in Foxborough.

Bettors looking for sportsbook promos , betting sites, and where to bet on the NFL for Week 5 can read more below, along with picks for some of the biggest games. Here are the top sportsbook promos for new users ahead of the 2025 Week 5 NFL schedule.