For decades, the biology of the intestinal stem cells was considered analogous to that of well-studied hematopoietic stem ...

Activation of cell death pathways typically leads to the irreversible destruction of the cell. However, in this issue of The ...

Mitochondria are dynamic organelles, the morphology of which results from an equilibrium between two opposing processes, fusion and fission. Mitochondrial fusion relies on dynamin‐related GTPases, the ...

EMBO Press encourages applying due care in interpreting bibliometric measures such as CiteScore, h5-Index and Journal Impact Factor among others. EMBO is a foundation signatory of the San Francisco ...

Clustered regularly interspaced short palindromic repeat (CRISPR) is a recently discovered adaptive prokaryotic immune system that provides acquired immunity against foreign nucleic acids by utilizing ...

The inner membrane of the mitochondrion folds inwards, forming the cristae. This folding allows a greater amount of membrane to be packed into the mitochondrion. The data in this study demonstrate ...

PIF4, a phytochrome-interacting bHLH factor, negatively regulates phytochrome B signaling in Arabidopsis.

3‐phosphoinositide dependent protein kinase‐1 (PDK1) plays a key role in regulating signalling pathways by activating AGC kinases such as PKB/Akt and S6K. Here we describe the 2.0 Å crystal structure ...

Genome rearrangements can take place by a process known as replication slippage or copy‐choice recombination. The slippage occurs between repeated sequences in both prokaryotes and eukaryotes, and is ...

A prominent response during the Drosophila host defence is the induction of proteolytic cascades, some of which lead to localized melanization of pathogen surfaces, while others activate one of the ...

MicroRNAs (miRNAs) constitute a large family of noncoding RNAs that function as guide molecules in diverse gene silencing pathways. Current efforts are focused on the regulatory function of miRNAs, ...

imageimageAuxin triggers NBR1-mediated selective autophagic degradation of ARF7 to modulate periodic root branching in Arabidopsis. ARF7 is selectively degraded via NBR1-mediated autophagy Auxin ...